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	<title>Pet Health Library - Marin Pet Hospital, San Rafael, CA &#187; Cats</title>
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		<title>How to Brush Your Pet&#8217;s Teeth</title>
		<link>http://marinpethospital.com/library/general/how-to-brush-your-pets-teeth-2/</link>
		<comments>http://marinpethospital.com/library/general/how-to-brush-your-pets-teeth-2/#comments</comments>
		<pubDate>Thu, 02 Feb 2012 22:19:03 +0000</pubDate>
		<dc:creator>MarinPet</dc:creator>
				<category><![CDATA[Cats]]></category>
		<category><![CDATA[Dental Care]]></category>
		<category><![CDATA[Dogs]]></category>
		<category><![CDATA[Feline Dental]]></category>
		<category><![CDATA[General]]></category>
		<category><![CDATA[Halitosis]]></category>
		<category><![CDATA[Helpful tips]]></category>
		<category><![CDATA[Hygiene]]></category>
		<category><![CDATA[Kidney Disease]]></category>
		<category><![CDATA[New Dog]]></category>
		<category><![CDATA[Precautions]]></category>

		<guid isPermaLink="false">http://marinpethospital.com/library/?p=721</guid>
		<description><![CDATA[In honor of National Veterinary Dental Month, we put together this short informational video to help you brush your pet&#8217;s teeth. This is a great preventative measure that we recommend to all of our patients!]]></description>
			<content:encoded><![CDATA[<p>In honor of National Veterinary Dental Month, we put together this short informational video to help you brush your pet&#8217;s teeth. This is a great preventative measure that we recommend to all of our patients!<br />
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		<title>Heat Stroke</title>
		<link>http://marinpethospital.com/library/cats/heat-stroke/</link>
		<comments>http://marinpethospital.com/library/cats/heat-stroke/#comments</comments>
		<pubDate>Thu, 15 Sep 2011 20:20:08 +0000</pubDate>
		<dc:creator>MarinPet</dc:creator>
				<category><![CDATA[Cats]]></category>
		<category><![CDATA[Dogs]]></category>
		<category><![CDATA[Heat Stroke]]></category>
		<category><![CDATA[Pocket Pets]]></category>

		<guid isPermaLink="false">http://marinpethospital.com/library/?p=693</guid>
		<description><![CDATA[Heat Stroke   If you think you get hot in the summer, think how it must feel to go through the hotter months wearing a fur coat. Heat stroke is a major concern in the spring and summer. Here are a few recommendations to prevent heat stroke: &#160; Make sure your pet always has access [...]]]></description>
			<content:encoded><![CDATA[<p align="center"><strong><span style="text-decoration: underline;">Heat Stroke</span></strong></p>
<p align="center"><strong><span style="text-decoration: underline;"> </span></strong></p>
<p>If you think you get hot in the summer, think how it must feel to go through the hotter months wearing a fur coat. Heat stroke is a major concern in the spring and summer. Here are a few recommendations to prevent heat stroke:</p>
<p>&nbsp;</p>
<ol>
<li>Make sure your pet always has access to shade.</li>
<li>Make sure your pet always has access to plenty of cool drinking water.</li>
<li>Exercise in the early morning or evening to avoid the hottest part of the day.</li>
<li>Never leave your unattended pet in the car.</li>
<li>Dogs are more susceptible to heat than humans. Therefore, if you are feeling parched and tired, your dog is even worse off.</li>
</ol>
<p>&nbsp;</p>
<p>The signs of heat stroke are excessive panting and lethargy in both dogs and cats.</p>
<p>&nbsp;</p>
<p>At our hospital the most common causes of heat stroke we see are going for a run in the middle of the day, and leaving a pet in the car. However, a pet left in the yard without any shade on a hot day is also quite susceptible.</p>
<p>&nbsp;</p>
<p>If you think your pet has heat stroke, use cool water (NOT ice water) to hose him down completely, and get your pet into the shade. Then call your vet.</p>
<p>&nbsp;</p>
<p>If you are able to take your pet’s rectal temperature, do so. Any body temperature over 102.6 is considered a fever. Any body temperature over 105.0 can cause metabolic and brain damage. Being able to relay your pet’s temperature to the veterinarian will help him decide if your pet needs medical attention. If your veterinarian decides that going into the hospital is not necessary, it is a good idea to take your pet’s temperature every half hour to make sure it is remains in the normal range, 99.8 to 102.6.</p>
<p>&nbsp;</p>
<p>Excessive heat can cause metabolic changes in your pet that can lead to death if not caught early enough. As is usual, we advocate that an ounce of prevention is worth a pound of cure.</p>
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		<title>Preventing and Solving Feline Housesoiling Problems</title>
		<link>http://marinpethospital.com/library/cats/preventing-and-solving-feline-housesoiling-problems/</link>
		<comments>http://marinpethospital.com/library/cats/preventing-and-solving-feline-housesoiling-problems/#comments</comments>
		<pubDate>Fri, 04 Feb 2011 20:57:43 +0000</pubDate>
		<dc:creator>admin</dc:creator>
				<category><![CDATA[Cat Behavior]]></category>
		<category><![CDATA[Cats]]></category>

		<guid isPermaLink="false">http://marinpethospital.com/library/?p=484</guid>
		<description><![CDATA[Nothing puts Kitty in the proverbial &#8220;doghouse&#8221; like a urine spot on the carpeting. Feline behaviorists find that inappropriate elimination problems (i.e. inconsistent litterbox use) top the list of the behavior aberrations with which they deal. It is also a major reason for cats to be surrendered to shelters or pounds. The good news is [...]]]></description>
			<content:encoded><![CDATA[<p>Nothing puts Kitty in the proverbial &#8220;doghouse&#8221; like a urine spot on the carpeting. Feline behaviorists find that inappropriate elimination problems (i.e. inconsistent litterbox use) top the list of the behavior aberrations with which they deal. It is also a major reason for cats to be surrendered to shelters or pounds. The good news is that housesoiling problems are preventable.</p>
<p>An understanding of what Kitty looks for in a desirable toilet area reveals preferences that are not unlike our own. For example, it must be clean, private, and easily accessible. They also have some requirements that are based on innate survival instincts&#8211;it must contain an easily-raked substrate and it must offer escape potential. Although our pets live in the safety and comfort of our homes, from their point of view these considerations are still vital to their well-being. This survival know-how is pre-programmed in your cat&#8217;s brain just as it was in his ancestor, the North African Wildcat, Felis Silvestris Libica&#8211;a cat who had unlimited access to a sandy substrate. By covering his waste he was able to elude detection by prey or potential predators. He was also alert to the danger of being caught in a vulnerable position so escape potential was a life-saving priority.</p>
<p>How does all this translate into setting up the ideal litterbox situation in your home? If we look at it from the cat&#8217;s point of view, we will make decisions that will be in harmony with the cat&#8217;s basic nature and it will optimize the likelihood that Kitty will find it acceptable. New products are popping up every day suggesting that they can take the mess, smell and work out of litterbox maintenance. For most people the litterbox regimen is the most unappealing aspect of cat ownership. Manufacturers of litter and litterboxes capitalize on this fact and offer a dizzying array of products meant to make this onerous task more agreeable. It can all be very confusing to the well-meaning, but not well-informed, cat owner. Should the litterbox be open or hooded? Should the litter be scented or fragrance-free? Should the litter be clumping or non-clumping? What about liners?</p>
<p>Decision-making should always be based on what is most natural from the cat&#8217;s standpoint. What would Kitty use if he were in the great outdoors? He would look for a soft, rakeable substrate (e.g. garden soil). There would be no artificial fragrance and of course, no liners. He would have plenty of room to perform his elimination ritual of sniffing, digging, squatting and turning around. A clean spot would be selected each time&#8211;at least six inches from the last location used.</p>
<p>Now how do we meet these requirements in the indoor environment? Let&#8217;s start with the litterbox. Select a box that is at least 16&#8243; x 22&#8243;. Avoid boxes that have rims that slant inward&#8211;they cut out a lot of interior space for the cat and are awkward for the cat to enter. The sides can be six inches deep unless the litterbox is for a small kitten or a handicapped cat. Some of the best litterboxes are not sold in pet stores but are labeled as &#8220;all-purpose tubs&#8221; in hardware stores. People whose cats like to throw the litter out of the box or who overshoot the box by not squatting down enough while urinating, have found that a large, high-sided storage box (minus the cover) works well to contain the mess. An entryway can be cut into one side to allow for easy access.</p>
<p>Hooded, or covered, litterboxes are popular with consumers, but if cats did the shopping, they would be left on the shelves. Humans do not want to see or smell what Kitty leaves behind in the litterbox, but for that matter, neither does Kitty. The hooded litterbox forces him to enter a cramped, cave-like structure that concentrates odors inside giving it an &#8220;outhouse&#8221; effect. Since the cat&#8217;s sense of smell is at least 14 times more sensitive than ours, this may be all it takes to send Kitty packing and in search of a fresher smelling toilet area&#8211;quite likely a corner of the diningroom. Unlike the hooded litterbox, the diningroom offers a spacious area with escape potential. This is especially important to felines in multi-cat families where litterbox ambushes are likely to occur.</p>
<p>Feline behaviorists agree that the ideal number of litterboxes in the household is one per cat, plus one. So even if there is just one cat in the home, there should be two litterboxes available to him. Many cats have a strong instinct to urinate in one area and defecate in another. The litterboxes should not be grouped together, but should be placed in different parts of the home, preferably on different floors. For people without a lot of extra room in their house, a corner litterbox is a space efficient way to fit in that extra box. <a title="www.eSmartCat.com" href="http://www.esmartcat.com/cgi-sys/cgiwrap/smartcat/sc/ref.cgi?storeid=*165594b9b032904406d2b95f6c&amp;name=Cats_International_Corner_Litterbox" target="_blank">SmartCat makes a well designed one</a>. Once the placement of the boxes has been decided, it is unwise to move them. Cats are very location oriented and will continue to visit an area previously used. The chosen locations must be convenient and cat-friendly. Cats like to see all around them when eliminating&#8211;especially the entrance to the room. If the litterbox is in a room that is very dark at night, it is a good idea to install a small night light. (Cats don&#8217;t see any better than we do in complete darkness, however, they see very well in low light.)</p>
<p>The true story of Susan and her cat Sammy illustrates the advisability of providing litterboxes on different floors of the home. Susan called the Cats International&#8217;s Feline Behavior Hotline one day when she was truly at the end of her rope. Her best friend and companion, Sammy, was totally out of control and she had no idea why. For three years he had never missed his litterbox which was located in her beautifully refinished basement. After arriving home from work this fateful day, she discovered to her horror that Sammy had eliminated all over the main floor of her house. She immediately whisked him off to the veterinarian, expecting to hear that a serious health condition had precipitated this bizarre behavior. To her relief and dismay, Sammy was pronounced perfectly healthy. &#8220;So why would he do this after years of impeccable litterbox manners?&#8221; Her question was followed by a series of probing questions from the counselor. During the course of the conversation, it became clear to the staff member that sometime during Susan&#8217;s absence Sammy had become frightened of going into the basement. She was reluctant to accept this explanation because he had always been happy and comfortable on the lower level.</p>
<p>Under protest Susan agreed to humor the counselor and check out to the basement to see if anything was amiss. The culprit was found lying not far from Sammy&#8217;s litterbox. It was an old scrolled up calendar that she had stored in the rafters. Our guess is that it took flight from its resting spot in the ceiling at the same time Sammy was attending to business. Convinced that a large predatory bird had invaded his sanctuary, he ran for his life. Poor Sammy. Poor Susan. This whole mess could have been avoided if there had been a second litterbox upstairs.</p>
<p>Cats are almost neurotic about their need to feel safe and secure while they are eliminating. They live in a sensory world entirely separate from ours. They hear things we can&#8217;t hear and they smell things we can&#8217;t smell. They are far more sensitive to vibration than we are. The slightest sound or disturbance can convince Kitty that his bathroom is a dangerous place&#8211;a furnace kicking in, clothes clanking in the dryer, a thunderstorm rattling the house. Even the family dog can make the cat nervous about using his litterbox, especially if Fido has access to the litterbox area. (Pet gates that Kitty can scoot under but which the dog cannot negotiate work well to keep the dog&#8217;s nose out of the cat&#8217;s business.)</p>
<p>The selection of a proper and appealing litter substrate is high on your cat&#8217;s priority list. To please Kitty the litter must be absorbent, unscented (cats dislike perfume), soft to the touch and familiar. In preference tests the majority of cats choose the sand-like clumping litter over the traditional non-clumping litter. This is not really so surprising if you have ever stepped barefoot on non-clumping litter. Ouch! Declawed cats in particular require the comfort afforded by the finer-grained scoopable litters. Everclean ES (formerly known as Everclean HD) is a litter that has proven to be popular with cats and their owners due to its superior ability to clump firmly. A good second choice is Scoop Away Fragrance Free. * Please note that Cats International does not recommend the use of clumping clay-based litters for kittens under the age of four months. Small kittens often ingest litter particles and this could pose a health risk. A non-clumping clay-based litter is fine for the little ones.</p>
<p>The advent of clumping litters has made the task of cleaning the litterbox much less onerous. However, there is a significant difference in the quality of clumping litters. The poorer quality litters break up easily when scooped, leaving particles of waste behind which will smell to the cat if not to you. These litters should be scooped daily and dumped completely at least a couple times a week. The more firmly clumping litters should also be scooped daily, but they do not have to be totally changed nearly as often&#8211;generally only when the litterbox itself requires washing. Since it is impossible to remove the urine from non-clumping litters, they should be scooped daily and dumped every other day (every day would be even better&#8211;would you want to use a toilet that was flushed only a few times a week?)</p>
<p>When it is time to wash the litterbox, use very hot water and dishwashing liquid. The use of bleach or other strong chemicals can leave a lingering scent in the box which might repel the cat. Even after a thorough cleaning, Kitty should still be able to detect his own unique scent. This is an important cue to the cat to return to this location the next time nature calls.</p>
<p>For most cats a litter depth of about three inches is satisfactory. With this amount of litter the urine usually does not stick to the bottom of the litterbox. Some cats find too much litter disturbing&#8211;much like sinking into quicksand. To discover your cat&#8217;s preference you can shift the litter in a large litterbox to one side so that there is a gradation of litter depth. Note the areas the cat prefers using and that may be your best clue as to the level of litter with which he is most comfortable.</p>
<p>At least 80% of the callers to our Feline Behavior Hotlines find that their housesoiling problems are completely resolved just by following our very specific recommendations for setting up and maintaining the litterboxes. It is important, however, that the cat owner never abruptly remove what is familiar to the cat. Cats don&#8217;t like changes but they do like choices; so instead, place the new litterbox and the new litter next to the old one until Kitty has decided to give it a try. If it becomes evident that it has become his clear favorite, then, and only then, can the old litter or litterbox be safely eliminated.</p>
<p>Sometimes our recommendations for litterbox improvements are met with, &#8220;but he has always had only one litterbox&#8221; or &#8220;he has always used the same litter&#8221;. Adam Bauknecht, the coordinator for our Madison Hotline offers this explanation, &#8220;All cats have a certain stress threshold. The level may vary among cats depending on their individual personalities and temperaments. When everything in the cat&#8217;s life is going smoothly, a few discomforts can be tolerated. If additional stressors enter the cats experience, stressors that cannot be eliminated, such as a new baby, houseguests, or the move to a new home, then suddenly the stress threshold is exceeded and Kitty&#8217;s misery is expressed in wet and not-so-wonderful ways. We can reduce the possibility of pushing Kitty over the top by eliminating the stressors over which we do have control (e.g. the litterbox annoyances). Then we can work to minimize the cat&#8217;s stress by gently introducing and desensitizing him to those elements in his life with which he must learn to cope.&#8221;</p>
<p>Cats urinating on beds, couches, carpeting, and even their owners&#8211;why do some cats enjoy scratching around in their litterboxes to the point of absurdity while others will use the litterbox only sporadically or will avoid it entirely as though it were a cat-eating monster? One desperate cat owner who called Cats International&#8217;s Behavior Hotline recently confessed that her cat, Mitzi, had not defecated in the litterbox for 11 years! Another cat owner hadn&#8217;t cleaned the litterbox for three months because her cat, Jed, wouldn&#8217;t go near it. She did, however, have to clean her bed linens on a daily basis because Jed reliably chose the bed for his bathroom, even when she was in it.</p>
<p>Not all cat owners are as long-suffering as these two, but all of them love their cats and want to see the end of a problem that is severely straining their relationship with their furry friend. Is it possible to correct housesoiling problems with any degree of certainty that they will not recur? The answer is &#8220;yes&#8221;, provided that the owner is willing to follow some important recommendations that will work with the cat&#8217;s basic nature and instincts to modify the behavior. It&#8217;s not difficult or expensive to solve problems of inappropriate elimination, but it does require a willingness to see life from the cat&#8217;s point of view.</p>
<p>Cats are pre-programmed to seek out an easily-raked substrate in which to eliminate. That&#8217;s why kittens need very little training. Just place them in a litterbox after a big meal and their instincts take over. If Kitty is not selecting the litterbox as her preferred area, then something is wrong. Perhaps she has a urinary or intestinal disorder that makes elimination uncontrollable or painful. She may be associating the litterbox with her discomfort and is therefore avoiding it. It is important to know that there may be no obvious symptoms of a health problem (cats are masters at hiding pain) other than the cat&#8217;s inconsistent use of the litterbox. It is always advisable to first rule out health considerations by taking Kitty to the veterinarian. In the case of inappropriate urination, a urinalysis is a good first procedure. If the problem is defecation, a fresh stool sample will be needed. Cats that are six months of age or older should be spayed or neutered to prevent urine marking. If the cat is already urine marking, sterilization at any age will eliminate the behavior in 90% of male cats and 95% of female cats.</p>
<p>If the problem is not Kitty&#8217;s health or hormones, then perhaps the litterbox is the problem. Is she eliminating near the litterbox, but not in it? If so, this may indicate that her intent was to use the litterbox, but for some reason, she just couldn&#8217;t bring herself to get into it. Usually this is because it is too dirty. Remember that cats are self-cleaning. They are not going to voluntarily step into moist or dirty litter that they will later have to clean off their paws or fur. (If they weren&#8217;t so fastidious, would we really want them to walk all over our homes and furnishings?) Since their senses are far more acute than ours, what is not offensive to us may be unbearable to them.</p>
<p>Have you changed litters? Is the new litter a different texture or scent? Being creatures of habit cats don&#8217;t appreciate sudden changes. Don&#8217;t surprise Kitty with the new litter you bought on sale today or she may surprise you with a present of her own. The money you saved on litter can be easily negated by the cost of cleaning products necessary to neutralize Kitty&#8217;s objection. If you want to introduce a new litter to your cat, place a litterbox containing the new litter next to her old litterbox. Add a scent cue to the new litter letting her know that it is intended for her use by taking a small amount of urine or stool from the old box and placing it in the new litter. If after several weeks she is using the new litter enthusiastically, then you can dispense with the old litter. However, if she tries it only occasionally, don&#8217;t risk offering the new litter exclusively. Remember that it is Kitty&#8217;s preferences, not yours, that count when it comes to the litterbox.</p>
<p>If the litter you are using is scented or if you are adding a fragranced deodorizer to the litter, you can immediately eliminate this irritant from the equation and at the same time improve your cat&#8217;s quality of life. Perfume is a very effective cat repellent.</p>
<p>The feel of the litter is also of great interest to the cat. An abrupt change from a sand-like litter to a pellet or crystal variety may shake her world (and soil yours!). Declawed cats tend to be especially sensitive to the litter texture. Most cats prefer the feel of the scoopable litters. Everclean ES (formerly known as Everclean HD) is a favorite with the cats and cat owners we have helped through our Behavior Hotlines. A good second choice is Scoop Away Fragrance Free. (We do not recommend clumping litters for kittens under the age of four months.)</p>
<p>Sometimes the solution to a housesoiling problem is as simple as adding another litterbox, keeping the boxes cleaner, removing the hoods, eliminating the liners, or offering a more natural litter substrate. When the litterbox improvements do not effect a change for the better, and the cat has been given a clean bill of health by the veterinarian, then it is time to consider other possible stressors.</p>
<p>Cats are very intelligent and sensitive little creatures that are highly reactive to their environment (some more so than others) and the stress target in cats is their bladders. Most people recognize the obvious stressors: a new baby, a new pet, remodeling or moving to a new home but the more subtle stressors may be overlooked: less attention from the cat&#8217;s favorite person due to a revised work schedule, infrequent or inadequate feedings, the scent of another cat on a visitor&#8217;s clothing, the sight of a stray cat from the window. We may not be aware of Kitty&#8217;s anxiety until we actually step in it. (This is a good time to remember that punishment never corrects inappropriate elimination problems, but it can make them worse by increasing the cat&#8217;s stress.)</p>
<p>Sometimes it takes the skill of a detective to determine what is upsetting the cat. The location of the urine or fecal marking may suggest a cause. For example, the cat who urinates on beds, clothes, or even directly in front of the owner, is often trying to communicate: 1) a painful health problem, 2) severe discomfort over an environmental stressor, or 3) distress relating to the individual whose belongings are being soiled. Ironically, cats often seek out the comforting scent of their favorite person when they are in pain or are stressed, but occasionally, a cat will selectively urinate on items belonging the individual who annoys or frightens the cat.</p>
<p>If the urine or fecal marking is located near a window or patio door, the culprit could be an stray cat. The sight of another animal so close to Kitty&#8217;s home base often triggers territorial marking, especially spraying. These problems are most common in spring when free-roaming cats are more likely to frequent yards and porches. When the windows are opened and the soft spring breeze wafts into the home, so does the urine scent of the local tom cat who left his wet calling card on the front door the night before.</p>
<p>There are a few creative products on the market designed to keep animal trespassers out of your yard. One of the newest ones is the Scarecrow&#8211;a clever devise that hooks up to your hose and works with a motion detector. As the animal approaches the forbidden area, the Scarecrow turns toward the offender and squirts him. (For more information check out www. scatmat.com.) A simpler solution is to keep the drapes or blinds shut at times outside animals are most likely to approach the house. If this happens only at night, then Kitty can be made comfortable in another area of the house away from the room with the view.</p>
<p>It may be the cats inside the home that are stressing the problem cat. There is a strong correlation between the number of cats in the household and spraying behavior. If there is competition for food, litterboxes, favorite resting areas, or attention from the owner, then there is likely to be some jockeying for dominance which often involves urine marking. In multi-cat families it is advisable to break up the areas of biological significance to the cats by having several feeding stations, by placing litterboxes in different parts of the house and by having lots of cozy hide-outs and resting areas, preferably in high places. Since the most important resource in the cat&#8217;s territory is the owner, the food provider, tensions can be greatly eased if each cat is given some individual attention during the day. If these measures are not sufficient to harmonize the relationships in the cat family, then it may be necessary to separate certain cats in different parts of the house or it may be in the cats best interests to re-home one or more of them.</p>
<p>One product that is effective in reducing or eliminating the incidence of territorial spraying is Feliway (Abbot Laboratories, Chicago, IL). This analogue of facial pheromones can be sprayed on prominent objects in the cat&#8217;s environment. When the cat sniffs the pheromone, the chemical message reads something like this, &#8220;All is well. This spot has been marked facially&#8211;no need for urine marking&#8221;. Feliway and directions for its use can be obtained through your veterinarian or from the Revival Animal Health Catalog (800-786-4751).</p>
<p>Another approach to reducing the anxiety of cats that are urine marking is drug therapy. It is most effective when used along with environmental modifications. The antianxiety drug, buspirone, has proven to be effective in cats from multi-cat households.</p>
<p>No housesoiling problem can be completely cured without addressing the need to clean and neutralize the soiled areas. If the scent lingers, it will be a constant reminder to the cat that this area was once used as a litterbox alternative and that it can be used again. In the case of a vertical urine mark (from spraying) the slowly fading scent will remind Kitty that his chemical message needs to be freshened. While many products promise to eliminate the odor of cat urine, few actually do. The Equalizer, a strong enzymatic product, is effective. If it sufficiently soaks into the carpeting or upholstery and reaches the urine, it will break it down and the smell will be gone. The Equalizer is sometimes sold in veterinary clinics, but it can also be purchased from the Revival Animal Health Catalog (800-786-4751).</p>
<p>To accurately identify the areas that need cleaning rent or purchase an ultra-violet light. The urine should fluoresce under the light, saving your nose from having to sniff out the problem spots. If you live with a group of cats and are unsure as to who is the culprit, you can give one of the suspects a small amount of fluorescein (obtainable from your veterinarian). This can be given orally to the cat each day. Under the ultraviolet light this cat&#8217;s urine will show up as a glowing green spot&#8211;with no harm to the cat (other than the stigma of having been identified as the perpetrator).</p>
<p>After the soiled areas have been thoroughly cleaned, place solid air fresheners in these locations to break Kitty&#8217;s habit of revisiting the scene of the crime. Experiment with different fragrances to discover which is most repelling to your cat. Keep in mind that many cats dislike a citrus smell. Spray repellents and plug-in air fresheners are not a good choice because it is difficult to determine at what point have lost their effectiveness and should be renewed.</p>
<p>Deterrents should remain in place for at least a month after Kitty has been using the litterbox regularly. When the treated areas are dry, a vinyl carpet runner can be placed (spike side up!) in the problem area. Small motion detectors are also very effective at keeping cats out of selected locations. Radio Shack sells a mini-motion detector for about $25 that works well with cats (Cat. No. 49-425). Don&#8217;t be tempted to protect the area by covering it with plastic as many cats particularly enjoy urinating on plastic.</p>
<p>This aversion conditioning along with the attraction strategy of providing a highly appealing litterbox near the previously soiled area solves a majority of inappropriate elimination problems. Some cats, however, require a short re-training or re-conditioning period. This is accomplished by restricting the cat to a comfortable room with its litterboxes, food and water (never near the litterboxes), bed and toys. Confinement should not be considered punishment and the cat should be regularly visited and played with during this re-training period. Any excursions outside the room should be carefully monitored and gradually lengthened until the cat can be left out with confidence. By affording no opportunity for deviant behavior, the proper behavior becomes routine.</p>
<p>Re-conditioning the cat to eliminate exclusively in designated areas is particularly useful in cases where the reason for the inconsistent litterbox use is not well understood. Kirsten Kranz, Cats International&#8217;s coordinator for the Racine/Kenosha Behavior Hotline frequently handles challenging housesoiling cases. Recently she received a cat from another state that had come to the attention of a caring individual who wished to save this friendly and unusual feline. &#8220;Matt&#8221; (Kirsten&#8217;s name for him) was born with a severe deformity. He has no lower legs or paws. He is amazingly proficient at moving himself around by utilizing the upper portion of his legs. Other than his locomotion problem, he is in all other respects a normal, healthy, happy, affectionate cat. He actually lived outside until he was discovered by a woman who kept him in a cage for several months where he virtually lived in his litterbox.</p>
<p>When Matt arrived at Kirsten&#8217;s home, he had no idea that the litterbox was the only designated spot for elimination. By understanding his history and carefully observing his substrate preferences Kirsten has within a week managed to train him to use the litterbox exclusively. She discovered that he did not like to eliminate on the bare linoleum floor however he would occasionally use the sandy substrate in the easy-access litterbox she provided for him. He would also eliminate on anything else that was left on the floor. By temporarily confining him to an area with only the bare floor, his litterbox, bed, food and water, she has successfully conditioned him to use his litterbox reliably. Matt is well on his was toward becoming an adoptable pet.</p>
<p>It is through careful observation that the clues are discovered that reveal the solutions to litterbox avoidance. No one is in a better position to make these discoveries than you, the pet owner. You know your cat&#8217;s unique personality and behavior patterns better than anyone else because you live with him. Take the time to notice his behavior in and around the litterbox. It will give you an idea of how he feels about his toilet. If he spends as little time as possible in the box&#8211;with hardly any digging or scratching in the litter&#8211;it could be that the substrate is offensive to him. If he uses the litter, but proceeds to scratch on the floor outside of the box, he may be finding the litterbox too small to accommodate this natural behavior.</p>
<p>Some cats have special needs and deserve extra consideration. For example, particular attention should be given to the unique problems of long-haired cats who may periodically find bits of stool sticking to their fur and may avoid the litterbox for that reason. They may also be disturbed by the fine-grained litter clinging to the tufts of fur on their paws&#8211;in which case they might be happier with a different textured substrate. (Trimming the fur in the problem areas may be all that is needed.) Declawed cats may also require special considerations as lingering paw sensitivity may force them to seek out smooth or soft surfaces for elimination purposes.</p>
<p>Whatever the reason for the inconsistent use of the litterbox, with a little work and a little patience, it can be solved!</p>
<h3>Summary</h3>
<p>Ten Steps to Solving Housesoiling Problems:</p>
<ol>
<li>Have the cat checked by a veterinarian to rule out the possibility that health problems are causing the litterbox avoidance.</li>
<li>Make sure that the litterbox situation is ideal&#8211;clean, natural, and convenient.</li>
<li>Identify possible stressors for the cat.</li>
<li>Eliminate the stressor, if possible. Otherwise, systematically desensitize the cat to the anxiety-producing stimulus. Drug therapy may be considered.</li>
<li>Thoroughly clean soiled areas with a strong enzymatic cleaner to remove any lingering odor.</li>
<li>Place deterrents in the problem areas for at least a month to break the cat&#8217;s habit of revisiting these spots.</li>
<li>If possible place a new litterbox in a location that is near the target area and where it can remain indefinitely.</li>
<li>Give the problem cat extra attention on a regular basis by practicing play therapy (interactive play with a fishing pole-type toy).</li>
<li>Don&#8217;t give up! There is always a humane solution for every behavior problem.</li>
<li>Call Cats International&#8217;s Behavior Hotline for help if necessary (262-375-8852).</li>
</ol>
<p><!-- #EndEditable --></p>
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		<title>Top Ten List to Preventing Litterbox Problems</title>
		<link>http://marinpethospital.com/library/cats/preventing-litterbox-problems/</link>
		<comments>http://marinpethospital.com/library/cats/preventing-litterbox-problems/#comments</comments>
		<pubDate>Fri, 04 Feb 2011 20:47:53 +0000</pubDate>
		<dc:creator>admin</dc:creator>
				<category><![CDATA[Cat Behavior]]></category>
		<category><![CDATA[Cats]]></category>

		<guid isPermaLink="false">http://marinpethospital.com/library/?p=477</guid>
		<description><![CDATA[Have your cat spayed or neutered at six months of age. Sexually mature, intact cats frequently use urine and feces to mark their territory. Neutering will correct the elimination problems in 90% of these cats. The rule of thumb for the number of litterboxes is: one per cat in the household, plus one. Extra litterboxes [...]]]></description>
			<content:encoded><![CDATA[<ol>
<li><a title="Corner Litterbox and Scoop by SmartCat" href="http://www.esmartcat.com/cgi-sys/cgiwrap/smartcat/sc/ref.cgi?storeid=*165594b9b032904406d2b95f6c&amp;name=Cats_International_Corner_Litterbox" target="_blank"><img src="http://www.catsinternational.org/images/photos/catsintphoto_012.jpg" border="0" alt="Corner Litterbox and Scoop by SmartCat" width="200" height="220" align="right" /></a>Have your cat spayed or neutered at six months of age. Sexually mature, intact cats frequently use urine and feces to mark their territory. Neutering will correct the elimination problems in 90% of these cats.</li>
<li>The rule of thumb for the number of litterboxes is: one per cat in the household, plus one. Extra litterboxes are necessary because some cats like to defecate in one and urinate in another. Others will not use a box that has already been used by another cat. Different areas for the litterboxes can prevent location-avoidance problems. If space is an issue, try a <a title="www.eSmartCat.com" href="http://www.esmartcat.com/cgi-sys/cgiwrap/smartcat/sc/ref.cgi?storeid=*165594b9b032904406d2b95f6c&amp;name=Cats_International_Corner_Litterbox" target="_blank">Corner Litterbox from SmartCat</a>.</li>
<li>Clean the litterboxes <strong>DAILY</strong>. The single most common reason for a cat&#8217;s refusal to use a litterbox is because the box is dirty. Non-clumping litter should be scooped daily and the litterbox emptied and washed every other day. Clumping litter should also be scooped daily and the litterbox washed when soiled. The cheaper clumping litters that break-up easily should be dumped out as frequently as the non-clumping litters. (Bacteria left in the litterbox will smell to the cat even if you can&#8217;t smell it.)</li>
<li>Choose a litter that appeals to the cat. Most cats prefer the texture of the sand-like scooping litters. Be sure to select a brand that clumps into a firm ball, making scooping easier and cleaner. (<a href="http://www.scoopaway.com/" target="_blank">Scoop Away Unscented</a> is excellent.) As a health precaution for kittens that might be prone to ingest the litter, use a non-clumping litter until the kitten is four months old.</li>
<li><strong>NEVER</strong> use scented litter. Perfumed, chemical scents repel cats. When you wash the litterbox, use hot water and a mild dishwashing liquid. Do not use harsh chemicals that will leave a lingering odor.</li>
<li>Do not use litterbox liners&#8211;they can be irritating to some cats. Also covered, or hooded litterboxes can be offensive to cats as they do not satisfy the cat&#8217;s need for escape potential when eliminating. They also trap the odor inside, creating an &#8220;outhouse effect&#8221;. The litterbox should be uncovered and at <em>least</em> 22&#8243; x 16&#8243; for an adult cat.</li>
<li>Place litterboxes in quiet, private places that are easily accessible to the cat and where it will not be disturbed by children or ambushed by other pets. Noisy areas near washing machines, furnaces, or under stairs, may frighten the cat away from the box. A house with several stories should have a litterbox on each floor. <strong>NEVER</strong> place litterboxes near food and water dishes.</li>
<li>While kittens have an innate predisposition to use an easily raked substrate as their litter, they may also choose other, more convenient, locations. You should limit their territory until they learn that the litterbox is the only acceptable place to eliminate. Praise and rewards will speed up the learning process. Like small children, they should not be expected to travel very far to find their toilet areas.</li>
<li>When introducing a new cat into the home, confine the cat to one room with its litterbox, bed, food and water, until the cat has used the litterbox several times and shows an interest in exploring the rest of the house. Once you have decided on the placement for the litterboxes in your house &#8212; <em>Don&#8217;t move them</em>!</li>
<li>Help your cat feel comfortable in his home territory. Play games with him, give him a massage, talk to him frequently. Give him positive and affectionate attention. A confident, secure, contented and relaxed cat does not need to relieve anxiety and stress by such extreme measures as urine or fecal marking.</li>
</ol>
<p>Article taken from <a href="http://www.catsinternational.org">www.catsinternational.org</a></p>
<p><!-- #EndEditable --></p>
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		<title>Cat Stopped Using the Litterbox?</title>
		<link>http://marinpethospital.com/library/cats/cat-stopped-using-the-litterbox/</link>
		<comments>http://marinpethospital.com/library/cats/cat-stopped-using-the-litterbox/#comments</comments>
		<pubDate>Fri, 04 Feb 2011 20:45:16 +0000</pubDate>
		<dc:creator>admin</dc:creator>
				<category><![CDATA[Cat Behavior]]></category>
		<category><![CDATA[Cats]]></category>

		<guid isPermaLink="false">http://marinpethospital.com/library/?p=474</guid>
		<description><![CDATA[Top ten reasons cat stop using the litterbox]]></description>
			<content:encoded><![CDATA[<h1>One in every 10 cats will have a litterbox lapse in his or her lifetime. Here are the most common reasons:</h1>
<ul>
<li>The cat is suffering from a urinary tract problem.</li>
<li>The cat experiences a bout of geriatric constipation.</li>
<li>The cat has not been spayed or neutered and is marking territory.</li>
<li>The caretaker does not keep the litterbox clean.</li>
<li>The litterbox has a hood on it (cats don’t like to feel trapped).</li>
<li>The owner uses disposable plastic liners.</li>
<li>The litter is scented (cats dislike perfume!).</li>
<li>The litter brand and type was suddenly changed.</li>
<li>The litterbox was washed with a harsh cleaning product.</li>
<li>The litter substrate is sharp and uncomfortable and it irritates the cat’s sensitive paw pads.</li>
<li>The cat has been declawed and finds digging in the litter painful.</li>
<li>There are not enough litterboxes in the house (1 per cat, plus 1).</li>
<li>The litterboxes are all in one area.</li>
<li>The cat is kept from using the litterbox by another family pet.</li>
<li>The location of the litterbox is too busy or too remote.</li>
<li>The owner suddenly changes the location of the litterbox.</li>
<li>The cat accidentally gets locked out of the room where the litterbox is located.</li>
<li>The cat was never properly trained to use the litterbox</li>
<li> in the first place.</li>
<li>The cat is stressed by a change in routine or the environment, including work schedule changes, overnight guests, new furniture, remodeling, outside animals seen through the window, etc.</li>
</ul>
<p>(The stress target in cats is the bladder.)</p>
<p>Article taken from Cats International.org</p>
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		<title>2010 Summer Reading List</title>
		<link>http://marinpethospital.com/library/uncategorized/2010-summer-reading-list/</link>
		<comments>http://marinpethospital.com/library/uncategorized/2010-summer-reading-list/#comments</comments>
		<pubDate>Fri, 14 May 2010 20:38:29 +0000</pubDate>
		<dc:creator>admin</dc:creator>
				<category><![CDATA[Cats]]></category>
		<category><![CDATA[Dogs]]></category>
		<category><![CDATA[Uncategorized]]></category>

		<guid isPermaLink="false">http://marinpethospital.com/library/?p=465</guid>
		<description><![CDATA[For all you avid readers out there, we compiled a book list of staff favorites for your summer reading pleasure. 1. A Dog&#8217;s Life by Peter Mayle 2. If Wishes Were Horses  by Anne McCaffrey 3. Simon&#8217;s Cat by Simon Tofield 4. How to be YOur Dog&#8217;s Best Friend by the Monks of Newskeet 5. [...]]]></description>
			<content:encoded><![CDATA[<p>For all you avid readers out there, we compiled a book list of staff favorites for your summer reading pleasure.</p>
<p>1.<span style="text-decoration: underline;"> A Dog&#8217;s Life</span> by Peter Mayle</p>
<p>2. <span style="text-decoration: underline;">If Wishes Were Horses</span>  by Anne McCaffrey</p>
<p>3. <span style="text-decoration: underline;">Simon&#8217;s Cat</span> by Simon Tofield</p>
<p>4. <span style="text-decoration: underline;">How to be YOur Dog&#8217;s Best Friend</span> by the Monks of Newskeet</p>
<p>5. <span style="text-decoration: underline;">The Art of Racing in the Rain</span> by Garth Stein</p>
<p>6.<span style="text-decoration: underline;"> All Creatures Great and Small</span> by James Herriot</p>
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		<title>Lyme Borreliosis</title>
		<link>http://marinpethospital.com/library/cats/lyme-borreliosis/</link>
		<comments>http://marinpethospital.com/library/cats/lyme-borreliosis/#comments</comments>
		<pubDate>Thu, 13 May 2010 19:58:00 +0000</pubDate>
		<dc:creator>admin</dc:creator>
				<category><![CDATA[Cats]]></category>
		<category><![CDATA[Disease]]></category>
		<category><![CDATA[Dogs]]></category>
		<category><![CDATA[Tick Disease]]></category>

		<guid isPermaLink="false">http://marinpethospital.com/library/?p=462</guid>
		<description><![CDATA[Lyme Borreliosis  Kathi Smith, RVT submitted 4/2003 Definition: A polysystemic tick transmitted spirochete disease found in the northeastern coastal states, southeast, Midwest, and western states. Etiologic Agent involved with Lyme Borreliosis is the spirochete, Borrelia burgdorferi Vector: The vector is the deer tick (Ixodes sammini in the Northeast, Ixodes scapularis in the southeast and Ixodes [...]]]></description>
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<td valign="top"><em><strong>Lyme Borreliosis</strong><br />
<strong> </strong></em>Kathi Smith, RVT</td>
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<p>submitted 4/2003</p>
<p><strong>Definition:</strong> A polysystemic tick transmitted spirochete disease found in the northeastern coastal states, southeast, Midwest, and western states.</p>
<p><strong>Etiologic Agent</strong> involved with Lyme Borreliosis is the spirochete, <em>Borrelia burgdorferi </em></p>
<p><strong>Vector: </strong>The vector is the deer tick (<em>Ixodes sammini</em> in the Northeast, <em>Ixodes scapularis</em> in the southeast and <em>Ixodes pacificus</em> in the western states and California). Other species of ticks (including the dog tick) and insects such as horseflies, deerflies, and mosquitoes can carry <em>B. burgdorferi</em>; however, only ticks have been linked with disease transmission. The route of infection is through the bite of an infected tick and requires 48 hours of attachment to the host. Mice are the main reservoirs due to the fact that they maintain the larval and nymph stages. Deer support the adult population but it is thought that they do not become infected by the spirochete. Birds however, may also be important reservoirs because they can transmit ticks and spirochetes over long distances.</p>
<p><strong>Clinical Signs </strong>associated with Lyme Borreliosis infection are typically subclinical, but may be septic or immune mediated. These include:</p>
<blockquote><p>· Sudden joint lameness (usually bilateral and involves the carpus) and evidence of severe pain, depression, fever, inappetence, lethargy, lymphadenopathy, limb shifting due to polyarthritis, acute progressive renal failure and protein losing glomerulonephropathy (especially in Labradors, and Golden Retrievers.), rheumatoid arthritis, meningitis, and myocarditis</p></blockquote>
<p><strong>Hematological and Biochemical Abnormalities are not usually seen with Lyme Borreliosis. </strong></p>
<blockquote><p>· Azotemia, protenuria, hematuria, pyuria, and tubular casts have been associated with dogs that have renal involvement of the infection.<br />
· Synovial fluid analyses are consistent for supportive polyarthritis with increased leukocyte numbers seen. Borrelia organisms are rarely isolated from joint fluid</p></blockquote>
<p><strong>Diagnosis of Lyme Borreliosis</strong>, like other tick borne diseases, can be difficult. There can be many other causes for the clinical signs seen with the disease and more than 50% of seropositive dogs remain asymptomatic while dogs with acute disease may be seronegative. To document seroconversion, retesting should be done in 3 to 4 weeks. Diagnosis should then be made on a combination of criteria:</p>
<blockquote><p>· Recent exposure to an endemic area<br />
· Detection of ticks on dog<br />
· Serologic test results, Enzyme-linked immunosorbent assay (ELISA) is considered more sensitive and specific than the indirect fluorescent antibody (IFA) test</p>
<blockquote><p>serum titers<br />
&lt; 1:28 = NEG<br />
1:128-1:256 = low +<br />
1:512 or &gt; = high +</p></blockquote>
<p>· Prompt response to antibiotic therapy<br />
· Immune-mediated diseases should be ruled<br />
· Radiographs and joint taps to rule out other causes of lameness</p></blockquote>
<p><strong>Treatment </strong>for Lyme Borreliosis consists of antibiotics and supportive care.</p>
<blockquote><p>· <strong>Doxycycline</strong> 10 mg/kg PO q 12 hours for 14-30 days<br />
· <strong>Cephalexin and Amoxicillin</strong> 22 mg/kg PO q 12 hours for 14-30 days<br />
· <strong>Azithromycin or Ceftriaxone</strong> should be used for refractory infection 5mg/kg PO q 12 hours<br />
· <strong>Anti-inflammatory drugs</strong> to reduce joint pain and swelling is debatable</p></blockquote>
<p><strong>Prognosis</strong> is good with proper treatment therapy. If the patient does not respond to antibiotic therapy in 7-10 days, the antibiotic should be changed.</p>
<p><strong>Prevention</strong> is through avoidance of tick-infested areas, control with the use of sprays, spot-ons, collars and vaccination (reserve vaccines for high risk dogs-outdoor, hunting, field trial)</p>
<p><a id="RelatedLinksBottomAnchor"></a><!--<mce:script type="text/javascript" mce_src="/Members/Related/RelatedHandler.ashx?cmd=default&amp;url=%2fMembers%2fCMS%2fMisc%2fVSPN%2fDefault.aspx%3fid%3d8155%26redirect%3d1" ></mce:script>&#8211;></p>
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<td colspan="2"><em>Date Published: April 29, 2003</em></td>
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		<title>Canine Pancreatitis</title>
		<link>http://marinpethospital.com/library/cats/canine-pancreatitis/</link>
		<comments>http://marinpethospital.com/library/cats/canine-pancreatitis/#comments</comments>
		<pubDate>Thu, 13 May 2010 19:39:55 +0000</pubDate>
		<dc:creator>admin</dc:creator>
				<category><![CDATA[Cats]]></category>
		<category><![CDATA[Disease]]></category>
		<category><![CDATA[Dogs]]></category>

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<td valign="top"><a href="http://www.veterinarypartner.com/Content.plx">Home</a> » Canine Pancreatitis</td>
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<td valign="bottom"><a href="http://www.veterinarypartner.com/Content.plx?P=SRC&amp;S=4&amp;SourceID=42&amp;EVetID=0">THE PET HEALTH LIBRARY</a><br />
By Wendy C. Brooks, DVM, DipABVP<br />
Educational Director, VeterinaryPartner.com</td>
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<p>Canine Pancreatitis<br />
 </p>
<p><strong>The Normal Pancreas and What It Does</strong></p>
<p>We eat food, chew it up into a slurry, and swallow it. It travels down the esophagus to the stomach where it is ground up further and enzymes are added to begin protein break-down (digestion). When the food particles are small enough, they are propelled into the small intestine for further digestive treatment and ultimately nutrient absorption. The small intestine has three portions: the duodenum that connects to the stomach, and the jejunum and ileum below. The jejunum and ileum are mostly involved in absorption but the duodenum, being so close to the stomach, is the site of further digestion.</p>
<p>There are two ducts that enter the duodenum near where the stomach contents enter. One duct is for bile, squirted in directly from the liver’s gall bladder. The bile serves to neutralize the acid that the stomach had added, to emulsify (or dissolve) dietary fats for absorption later in the tract, and also to excrete some toxins. The other duct is the pancreatic duct, which squirts in more digestive enzymes so as to break down starches and more protein.</p>
<p>The pancreas is a pale pink glandular organ that nestles cozily just under the stomach and along the duodenum. As a glandular organ, the pancreas is all about secretion, and it has two main jobs: the first job is the secretion of digestive enzymes to help us break down the food we eat, the second job being secretion of insulin and glucagon (to regulate sugar metabolism). The digestive enzymes are the part of the story that concerns us in pancreatitis.</p>
<p><strong>Pancreatitis Is Inflammation of the Pancreas</strong></p>
<p>In pancreatitis, inflammation disrupts the normal integrity of the pancreas. Digestive enzymes that are normally safely stored in granules are released prematurely where they digest the body itself. The result can be a metabolic catastrophe. The living tissue becomes further inflamed and the tissue damage quickly involves the adjacent liver. Toxins released from this orgy of tissue destruction are released into the circulation and can cause a body-wide inflammatory response. If the pancreas is affected so as to disrupt its ability to produce insulin, diabetes mellitus can result; this diabetes can be either temporary or permanent.</p>
<p>Special disasters include the disruption of “surfactants” in the lung tissue that normally keep the tiny air-filled alveoli from collapsing after each exhaled breath. Without surfactants, the alveoli close up and respiratory failure results.</p>
<p>Also, there is a syndrome called Weber-Christian syndrome in which fats throughout the body are destroyed.</p>
<p>Pancreatitis is one of the chief risk factors for the development of what is called disseminated intravascular coagulation, or DIC, which is basically a massive uncoupling of normal blood clotting and clot dissolving mechanisms. This leads to abnormal simultaneous bleeding and clotting of blood throughout the body.</p>
<p>Pancreatic encephalopathy (brain damage) can occur if the fats protecting the central nervous system become digested.</p>
<p><strong><em>The good news is that most commonly the inflammation is confined to the area of the liver and pancreas but even with this limitation, pancreatitis can be painful and life-threatening.</em></strong></p>
<p><strong><em>Pancreatitis can be acute or chronic, mild or severe</em></strong>.</p>
<p><strong>What Causes Pancreatitis</strong></p>
<p>In most cases we never find out but we do know some events that can cause pancreatitis:</p>
<p>• Reflux of duodenal contents into the pancreatic duct. The pancreas has numerous safety mechanisms to prevent self-digestion. One of these mechanisms is the fact that the enzymes it creates are stored in an inactive form. They are harmless until they are mixed with activating enzymes. The strongest activating enzymes are made by duodenal cells, which means that the digestive enzymes do not actually activate until they are out of the pancreas and mixing with food in the duodenum. If duodenal fluids backwash up the pancreatic duct and into the pancreas, enzymes are prematurely activated and pancreatitis results. This is apparently the most common pancreatitis mechanism in humans, though it is not very common in veterinary patients.<br />
• Concurrent hormonal imbalance predisposes a dog to pancreatitis. Such conditions include: <a href="http://www.veterinarypartner.com/Content.plx?P=A&amp;A=631&amp;S=0&amp;EVetID=0" target="_blank">diabetes</a>, <a href="http://www.veterinarypartner.com/Content.plx?P=A&amp;A=461&amp;S=0&amp;EVetID=0" target="_blank">hypothyroidism</a>, and <a href="http://www.veterinarypartner.com/Content.plx?P=A&amp;A=1732&amp;S=0&amp;EVetID=0" target="_blank">hypercalcemia</a>. The first two conditions are associated with altered fat metabolism that predisposes to pancreatitis, and the latter condition involves elevated blood calcium that activates stored digestive enzymes.<br />
• Use of certain drugs can predispose to pancreatitis (sulfa-containing antibiotics such as <a href="http://www.veterinarypartner.com/Content.plx?P=A&amp;A=617&amp;S=0&amp;EVetID=0" target="_blank">trimethoprim sulfa</a> or chemotherapy agents such as <a href="http://www.veterinarypartner.com/Content.plx?P=A&amp;A=511&amp;S=0&amp;EVetID=0" target="_blank">azathioprine</a>).<br />
• Trauma to the pancreas as from a car accident or even surgical manipulation can cause inflammation and thus pancreatitis.</p>
<p><strong><em>Miniature Schnauzers are predisposed to pancreatitis as they commonly have altered fat metabolism.</em></strong></p>
<p><strong>Signs of Pancreatitis</strong></p>
<p>The classical signs in dogs are appetite loss, vomiting, diarrhea, painful abdomen, and fever.</p>
<p><strong>Making the Diagnosis</strong></p>
<p>A reliable blood test has been lacking for this disease. Traditionally, blood levels of amylase and lipase (two pancreatic enzymes) have been used. When their levels are especially high, this is felt to be a reasonable sign of pancreatitis, but still these tests are not as sensitive or specific as we would prefer. They can elevate dramatically with corticosteroid use, with intestinal perforation, kidney disease, or even dehydration. Some experts advocate measuring lipase and amylase on fluid from the belly rather than on blood but this has not been fully investigated and is somewhat invasive.</p>
<p>A newer test called the PLI or pancreatic lipase immunoreactivity test has come to be important. Lipase is one of the pancreatic digestive enzymes and small traces are normally present in the circulation. These levels jump dramatically in pancreatitis and the diagnosis can be confirmed with a less expensive and non-invasive test. A regular lipase level measures all forms of lipase, not just those of a pancreatic source; this is test is specific for pancreatic lipase. The problem is that technology needed to run this test is unique and the test can only been run in certain facilities on certain days. Results are not necessarily available rapidly enough to help a very sick patient.</p>
<p>More recently a new test called the SPEC cPL (specific canine pancreatic lipase) test has come to be the test of choice. This test is a newer generation immunological test for canine pancreatic lipase and can be run overnight by a reference lab. This test is able to detect 83% of pancreatitis cases (the test is 83% sensitive) and excludes other possible diseases in 98% of cases (i.e., the test is 98% specific for pancreatitis). There is no comparable test for cats at this time.</p>
<p>Radiographs can show a widening of the angle of the duodenum against the stomach, which indicates a swelling of the pancreas. Most veterinary hospitals have the ability to take radiographs but this type of imaging is not very sensitive in detecting pancreatitis and only is able to find 24% of cases.</p>
<p>Ultrasound, on the other hand, detected 68% of cases and provides the opportunity to image other organs and even collect fluid from the belly easily. When one balances rapid results and accuracy, this test may be the best.</p>
<p>In some cases, surgical exploration is the only way to make the correct diagnosis.</p>
<p><strong>Treatment</strong></p>
<p>The passage of food through the duodenum is a strong stimulus to the pancreas. In the treatment of canine pancreatitis we do not want any stimulation of the pancreas; we want the pancreas to rest. This means no food and no water for 2 to 3 days (IV fluid support prevents dehydration).</p>
<p>Fluid support will generally require potassium supplementation as potassium depletes in pancreatitis. Blood pH must be tracked as well. A critical patient with pancreatitis will need 24 hour care and blood test monitoring several times a day. A plasma transfusion represents a special type of fluid therapy and helps provide special proteins that inhibit pancreatic enzymes. Whether or not the protection afforded by plasma is real or theoretical is still being worked out but since it is difficult to go wrong with a plasma transfusion, do not be surprised if your veterinarian uses this approach.</p>
<p>Pancreatitis is a painful condition and pain management is not only humane but important in recovery. Untreated pain affects the immune system and increases mortality. Injectable pain medications, <a href="http://www.veterinarypartner.com/Content.plx?P=A&amp;A=534&amp;S=0&amp;EVetID=0" target="_blank">fentanyl patches</a>, and even continuous drips can be used effectively to control pain. Additional medications to control nausea are also commonly used in the management of this condition. Antibiotics are often used because even though pancreatitis is not a bacterial disease, bacterial invasion from the diseased intestine is a common occurrence.</p>
<p>Once the patient has started to eat again, a low fat diet (such as one of the prescription high fiber diets) is important to minimize pancreatic stimulation. Since there is potential for the pancreas to always have a chronic smoldering bit of inflammation, long-term use of a low-fat diet is likely to be recommended.</p>
<p><strong>Beware of Diabetes Mellitus</strong></p>
<p>When the inflammation subsides in the pancreas, some scarring is inevitable. When 80% of the pancreas is damaged, insulin cannot be produced, and diabetes mellitus results. This may or may not be permanent depending on the capacity for the pancreas’ tissue to recover. See more information on the management of <a href="http://www.veterinarypartner.com/Content.plx?P=A&amp;A=631&amp;S=0&amp;EVetID=0" target="_blank">diabetes mellitus</a>.</p>
<p><em>Date Published: 1/2/2006 12:27:00 PM<br />
</em></p>
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		<title>Dietary Therapy of Renal Failure</title>
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		<pubDate>Thu, 13 May 2010 19:37:07 +0000</pubDate>
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		<description><![CDATA[  THE PET HEALTH LIBRARY By Wendy C. Brooks, DVM, DipABVP Educational Director, VeterinaryPartner.com          Dietary Therapy of Renal Failure Related Articles A Chronic Renal (Kidney) Failure Center Anemia: Inadequate Red Blood Cells Anorexia Calcium Phosphorus Balance Chronic Renal Failure Links Fluid Therapy Glomerulonephritis High Blood Pressure (Systemic Hypertension) in our Pets Kidney [...]]]></description>
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<td valign="bottom"><a href="http://www.veterinarypartner.com/Content.plx?P=SRC&amp;S=4&amp;SourceID=42&amp;EVetID=0">THE PET HEALTH LIBRARY</a><br />
By Wendy C. Brooks, DVM, DipABVP<br />
Educational Director, VeterinaryPartner.com</td>
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<p>Dietary Therapy of Renal Failure</p>
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<td bgcolor="#9c9cb3">Related Articles</td>
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<p>There are many aspects of kidney failure that require attention. Diet can be used to help in many ways and we are lucky to have commercially available diets made specifically for renal patients. There are even diets made for different stages of kidney failure. The goal of therapy, dietary or otherwise, is to prevent or at least postpone advanced uremia (poisoning by toxins that the kidneys could not adequately remove) and extend life expectancy.<br />
In one famous study where 38 dogs in kidney failure were tracked for 2 years, dietary therapy reduced the risk of dying by 69% over dogs allowed to continue eating regular dog food.</p>
<p>Another study in dogs showed that beginning the renal diet when the creatinine was between 2.0 and 3.1 delayed the onset of uremic crisis by 5 months.</p>
<p>A study of 50 cats with stable naturally occurring renal failure were divided into two groups, one receiving renal diet and the other receiving regular food. The cats on the renal diet survived over twice as long as the others.</p>
<p>Clearly there is tremendous benefit to the patient in switching to a therapeutic renal diet. Unfortunately, these diets tend to be blander than what the pet may be used to and they are not always acceptable to the pet.</p>
<ul>
<li>Do not attempt to starve the pet into eating the new food. Change more gradually.</li>
<li>Consider using another brand that might have a different flavor. Remember, therapeutic foods are guaranteed so that even opened bags can be returned for a full refund.</li>
</ul>
<p>Let’s review some basic features of a desired diet. There are many misconceptions about an appropriate diet for renal disease. In fact, what dietary modifications should be made depend on the stage of renal disease. Some basic desired qualities in a renal diet are:</p>
<ul>
<li>Protein restriction</li>
<li>Phosphate restriction</li>
<li>Sodium restriction</li>
<li>Supplementation with omega-3 fatty acids</li>
</ul>
<p><strong>Low Protein</strong></p>
<p>Since a number of renal toxins come from the metabolism of protein, one way to give the kidneys less work to do is to eat less protein. How much less protein depends on how serious the kidney disease is. Older animals tend to require a higher dietary protein level in general when compared to their younger counterparts. Protein also adds palatability to the food so that if we try to restrict protein too much we may end up with a pet who will not eat at all.</p>
<p>Further, there is a metabolic requirement for protein below which a diet cannot dip. This has led to diets with differing protein restrictions to fit with different stages of disease, less restriction for earlier stages.</p>
<ul>
<li>There is no protective value to restricting protein prior to the onset of kidney failure.</li>
<li>High protein diets do not cause kidney failure (though they certainly make the patient worse after kidney failure is present).</li>
</ul>
<p><strong>Phosphorus Restriction</strong></p>
<p>This is an important part of a renal diet since phosphorus balance is crucial. Phosphorus comes into the body via the diet and leaves the body via the kidney, only in renal failure phosphorus is not well removed as it is supposed to. Obviously using less phosphorus in the diet may be adequate to keep the blood phosphorus levels normal, thus balancing the intake with the output, but sometimes addition of medication (i.e. a phosphate binder) is needed to further reduce intake. Restricting dietary phosphate has been shown to slow the progression of renal disease.</p>
<p><strong><em>If the goal phosphorus level has not been achieved in 2 to 4 weeks after starting the renal diet, a phosphorus binder should be utilized.</em></strong></p>
<p><strong>Omega 3 Fatty Acids</strong></p>
<p>Studies suggest that kidney failure patients taking omega 3 fatty acids are likely to live longer than patients who do not take them. This has led to the supplementation of most renal diets with fish oils. The full import of fatty acid supplementation is still being worked out.</p>
<p>Other dietary features include B vitamin supplementation (since the damaged kidneys tend to lose excess B complex), which have non-acidifying features to help control acidosis.</p>
<p><strong>At What Point Should a Special Diet be Started?</strong></p>
<p>This has been a controversial question for a long time. For many animals, changing diet to a less palatable food represents a definite reduction in life quality. There was some thinking that we are changing the diet too soon. On the other hand, if a pet is in a more advanced state of disease before the switch is made, the pet will be much less willing to change to a food of less palatability. The companies that make these foods have put a great deal of research into improving palatability over the years, which has helped tremendously and now the International Renal Interest Society finally has guidelines.</p>
<p><strong><em>They recommend changing the diet to a renal food when a dog’s creatinine level is in the 2.1-5 mg/dl range (Stage III renal failure). For cats, the diet should change when the creatinine reaches approximately 2.0 mg/dl (middle Stage II renal failure).</em></strong></p>
<p>These guidelines allow the patient to benefit the most from the preventive advantages of the diet. If the pet finds the diet palatable then there should be no life quality issues with changing foods.<br />
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<p><strong>Home Cooking a Renal Diet</strong></p>
<p>Home cooking an appropriate renal diet is a complicated task but it can be done. Because different pets experience different problems with their renal disease (potassium depletion or not, pH issues or not, different degrees of phosphorus restriction needed, etc.), the diet should ideally be tailored to the individual.</p>
<p>Your veterinarian can get you an appropriate recipe through <a href="http://www.balanceit.com/" target="_blank">www.balanceit.com</a>. (Because these are therapeutic diet formulas, you cannot access them on your own.)</p>
<p>Several recipes have been published by Dr. Donald Strombeck, one of the internal medicine specialists at the University of California at Davis. These recipes can be viewed at:</p>
<p><a href="http://users.ameritech.net/critterz/crf_recipes.htm#Strombeck%27s%20recipes" target="_blank">http://users.ameritech.net/critterz/crf_recipes.htm#Strombeck%27s%20recipes</a></p>
<p>We cannot vouch for other recipes found on this site but can say that often published recipes prove nutritionally incomplete when scrutinized. The Strombeck recipes are complete and balanced.</p>
<p>For more detailed recipe and expert adjustments, a veterinary nutritionist can be consulted. There are several university nutrition departments that offer this service but we have found the best service from a private company at<br />
<a href="http://www.petdiets.com/" target="_blank">www.petdiets.com</a>.</p>
<p>Expect a consultation with a veterinary nutritionist to cost anywhere from $150 to $200.</p>
<p><em>Date Published: 7/30/2007 10:53:00 AM<br />
</em></p>
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		<title>Glomerulonephritis</title>
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		<pubDate>Thu, 13 May 2010 19:35:01 +0000</pubDate>
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		<description><![CDATA[  THE PET HEALTH LIBRARY By Wendy C. Brooks, DVM, DipABVP Educational Director, VeterinaryPartner.com          Glomerulonephritis Related Articles A Chronic Renal (Kidney) Failure Center Anemia: Inadequate Red Blood Cells Anorexia Calcium Phosphorus Balance Chronic Renal Failure Links Dietary Therapy of Renal Failure Fluid Therapy High Blood Pressure (Systemic Hypertension) in our Pets Kidney [...]]]></description>
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<td valign="bottom"><a href="http://www.veterinarypartner.com/Content.plx?P=SRC&amp;S=4&amp;SourceID=42&amp;EVetID=0">THE PET HEALTH LIBRARY</a><br />
By Wendy C. Brooks, DVM, DipABVP<br />
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<p>Glomerulonephritis</p>
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<td bgcolor="#9c9cb3">Related Articles</td>
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<td><a href="http://www.veterinarypartner.com/Content.plx?P=A&amp;C=&amp;A=2633&amp;SourceID=">A Chronic Renal (Kidney) Failure Center</a></td>
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<td valign="top"><img src="http://www.veterinarypartner.com/Images/RelatedArticlesIcon.gif" border="0" alt="" width="16" height="16" align="top" /></td>
<td><a href="http://www.veterinarypartner.com/Content.plx?P=A&amp;C=&amp;A=2595&amp;SourceID=">Anemia: Inadequate Red Blood Cells</a></td>
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<td><a href="http://www.veterinarypartner.com/Content.plx?P=A&amp;C=&amp;A=2509&amp;SourceID=">Anorexia</a></td>
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<td><a href="http://www.veterinarypartner.com/Content.plx?P=A&amp;C=&amp;A=2622&amp;SourceID=">Calcium Phosphorus Balance</a></td>
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<td><a href="http://www.veterinarypartner.com/Content.plx?P=A&amp;C=&amp;A=2629&amp;SourceID=">Chronic Renal Failure Links</a></td>
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<td><a href="http://www.veterinarypartner.com/Content.plx?P=A&amp;C=&amp;A=2615&amp;SourceID=">Dietary Therapy of Renal Failure </a></td>
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<td><a href="http://www.veterinarypartner.com/Content.plx?P=A&amp;C=&amp;A=2596&amp;SourceID=">Fluid Therapy</a></td>
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<td><a href="http://www.veterinarypartner.com/Content.plx?P=A&amp;C=&amp;A=1216&amp;SourceID=">High Blood Pressure (Systemic Hypertension) in our Pets</a></td>
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<td><a href="http://www.veterinarypartner.com/Content.plx?P=A&amp;C=&amp;A=1749&amp;SourceID=">Kidney Dialysis: Is it for your Pet?</a></td>
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<td><a href="http://www.veterinarypartner.com/Content.plx?P=A&amp;C=&amp;A=572&amp;SourceID=">Kidney Failure: Where to Begin</a></td>
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<td><a href="http://www.veterinarypartner.com/Content.plx?P=A&amp;C=&amp;A=1349&amp;SourceID=">Kidney Transplants for Cats and Dogs</a></td>
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<p><strong>(Renal Protein Loss Due to Inflammation)</strong></p>
<p>Most of the time when kidney disease is discussed, renal insufficiency or chronic kidney failure is the subject. In renal failure, the kidney loses its ability to conserve the body’s water as it removes the body’s daily toxin build up. Excessive water consumption is seen as an early sign of trouble as large amounts of water are required to make enough urine. Eventually toxins build up despite increased water consumption. Weight loss ensues. The classical metabolic changes that result are collectively called uremia or uremic poisoning.</p>
<p>Glomerular disease is different. Glomerular disease represents more of a filtration problem rather than a failure to excrete harmful toxins; in fact, glomerular disease is all about losing protein inappropriately through the kidneys. While it is certainly possible to have uremia without glomerular disease and glomerular disease without uremia, in many cases glomerular disease seems to represent a situation that can progress to uremia.</p>
<p><strong>What Is a Glomerulus Anyway?</strong></p>
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<p>This illustration shows the nephron, which is the functional unit of the kidney. The kidneys have thousands upon thousands of these and they serve to filter the blood, add in toxins to get rid of, and balance the blood’s electrolytes and pH by adding and subtracting salts. The round tuft-like structure at the head of the nephron is the glomerulus, where blood is filtered.</p>
<p>The delicate membranes of the glomerulus, allow salts and very small molecules to pass through while cells and large molecules (like proteins) stay in the blood. Later areas in the nephron balance the salts and small molecules to make sure we keep and dump them in appropriate amounts but the glomerulus is the filter that allows our body’s blood proteins to be conserved. Let’s take a closer look:</p>
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<p>The glomerulus is the microscopic kidney area that separates urine from blood. Blood comes in the afferent arteriole, is filtered in a tuft of capillaries, and then exits through the efferent arteriole. The fluid that has been separated out is channeled into the tubules of the nephron for further treatment. Let us emphasize that the filtration membranes are very delicate.</p>
<p>When glomerular disease exists, holes are punched out in this filtration system allowing large molecules (like the proteins that a body needs to keep) to enter the urine flow and be urinated away into oblivion.</p>
<p><strong>How Does the Glomerulus Get Leaky?</strong></p>
<p>Sources of chronic inflammation are believed to be the ultimate cause of the problem. The chronic inflammatory state leads to the circulation of antigen:antibody complexes in the blood and these complexes stick in delicate glomerular membranes like flies in fly paper. Once stuck there, they call in other inflammatory cells and soon a hole is eaten into the membrane by the ensuing reaction. The holes in the filtration membranes are big enough for proteins to traverse.</p>
<p>There are many are many possible sources of chronic inflammation which could be generating antigen:antibody complexes. Chronic ear or skin infections could be the cause. Long-standing dental disease could do it. A latent more internal infection might be the cause (such as <a href="http://www.veterinarypartner.com/Content.plx?P=A&amp;A=1196&amp;S=0&amp;EVetID=0" target="_blank">heartworm</a>, <a href="http://www.veterinarypartner.com/Content.plx?P=A&amp;A=681&amp;S=0&amp;EVetID=0" target="_blank">feline infectious peritonitis</a>, prostate infection, or <a href="http://www.veterinarypartner.com/Content.plx?P=A&amp;A=2103&amp;S=0&amp;EVetID=0" target="_blank">Ehrlichiosis</a>). Even a tumor might generate enough of the immune system’s attention to lead to this sort of reaction.</p>
<p><strong>Kidney failure is one thing but when it is compounded by glomerular protein loss,<br />
survival is substantially reduced and prognosis is much worse.</strong></p>
<p><strong>How Is the Diagnosis Made?</strong></p>
<p>There are several common scenarios that might lead to the diagnosis of glomerular disease.</p>
<p><em>Protein found in a routine urinalysis</em><br />
A urinalysis examines a urine sample for some of its chemical contents and properties. Protein content is one of the parameters that are checked and semi-quantified in a small, medium or large amount. On a urinalysis report this will be designated as “+, ++, or +++.”</p>
<p>This seems like it would be easy enough to interpret but unfortunately there is more to the story. A small amount of protein in a well-concentrated sample may be very normal while the same amount of protein a dilute sample would be highly significant. How dilute or concentrated the urine is depends on the patient’s water consumption and we need a method to examine urine protein that is independent of the patient’s water consumption.</p>
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<p>To complicate matters more, protein in urine may be a reflection of inflammation or infection in the urinary bladder (or even blood contamination of the sample) and not be related to the kidney at all. To determine what is going on, there are two tests that your veterinarian may discuss:</p>
<p>• Urine culture<br />
• Urine Protein:Creatinine ratio</p>
<p>The culture of the urine should find any latent infections (infection and its associated inflammation easily increases protein in the bladder). The urine protein:creatinine ratio quantifies the amount of protein loss in a way that is not dependent on the patient’s water consumption. It is helpful to do the culture first as a bladder infection will elevate the urine protein:creatinine ratio well into the abnormal range and lead to the wrong diagnosis if infection is not ruled out.</p>
<p>If the urine sediment is active, meaning there are inflammatory cells in the sample then the patient most likely has infection and culture should be pursued. If the urine is dilute from the patient’s excess water consumption, it may be prudent to culture the urine to rule out a more latent infection. Alternatively, if the sediment is not active (and especially if the sample is not also dilute), a recheck urine sample in a couple of weeks to see if the urine protein is persisting might also be a fair idea. If there is still protein in the urine 2 to 4 weeks later, further tests are definitely in order.</p>
<p><strong>Screening for Protein Loss After Diagnosing Kidney Failure</strong></p>
<p>After kidney failure has been discovered, if urine testing has not yet been done, performing urine tests can lead to important additional information. Again we come to the same two tests:</p>
<p>• Urine culture<br />
• Urine protein:creatinine ratio</p>
<p>In the kidney failure patient, urine is generally very dilute because failure includes inability to concentrate urine/conserve water. This means that urinalysis clues that there is an infection (visible bacteria, white blood cells etc.) will be diluted out. The only way to find a latent infection is to culture the sample. If infection and kidney failure are present together, there is a good chance that the infection is inside the kidney. This means the antibiotic course must be much longer (4-6 weeks) than it would be for a simple bladder infection. It also means there may be potential for the kidney to heal with time and for function to be regained. Prognosis thus improves with documented infection.</p>
<p>On the other hand, glomerular disease accompanying kidney failure is bad news. The kidney insufficiency is likely to progress much faster when the urine protein:creatinine ratio is abnormal.</p>
<p><strong>Low Blood Albumin Level Found on a Blood Panel</strong></p>
<p>Albumin is one of those proteins that the body really wants to conserve. There are plenty of substances the body needs to circulate that simply are not water soluble, which means they will not simply dissolve in the bloodstream and be pumped around by the heart. Substances that will not dissolve in water bind to albumin, and the albumin carries them around like passengers on a subway train. Albumin also is important in keeping water in the bloodstream. (This sounds odd but blood is basically a liquid and without enough water it sludges and clots abnormally.) Further, if water is not held in the vasculature, it leaks into other body cavities such as the chest and abdomen, filling these cavities with liquid.</p>
<p>There are few ways that albumin can be depleted.</p>
<p>• When an inflammatory process occurs and globulin levels rise due to antibody production, albumin levels will drop in compensation so that the overall blood protein level does not get too high. This is normal compensation and should not lead to a dangerously low albumin level.<br />
• Albumin can be lost from the intestinal tract in diseases called protein-losing enteropathies. These conditions tend to lose albumin as well as other blood proteins through GI tract leakage.<br />
• Albumin is a product of the liver. If the liver fails, there may not be adequate albumin produced.<br />
• Albumin can be lost through the holes in the kidney membranes caused by glomerular disease. Fairly advanced glomerular disease is required to produce an actual drop in blood albumin. One would need to beware of nephrotic syndrome (see below) and treatment would be needed.</p>
<ul>
<li>Urine protein:creatinine ratio of &lt;1.0 in a stable animal with normal kidney function<br />
tests (normal blood creatinine) can simply be periodically monitored.</li>
<li>A urine protein:creatinine ratio of 1-2 warrants investigation into a possible underlying cause.</li>
<li>A urine protein:creatinine ratio &gt;2 warrants not only investigation but also intervention.<br />
The International Renal Interest Society classifies the urine protein:creatinine ratio a little<br />
 differently for animals that are azotemic (have an elevated blood creatinine level):<br />
     • Ratios &lt;0.2 are considered normal<br />
     • Ratios of 0.2-0.5 in dogs and 0.2-0.4 in cats are considered borderline proteinuric and warrant a test 2 months to see if the condition is progressing.<br />
     • Ratios &gt;0.5 in dogs and &gt;0.4 in cats are considered proteinuric and require intervention.</li>
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<p>A biopsy of the kidney is needed to absolutely confirm the diagnosis of glomerulonephritis and classify the glomerular inflammation further. This is an invasive and potentially risky procedure and recently the usefulness of the information gleaned from biopsy has been questioned.</p>
<p>It is much more practical to monitor the urine protein:creatinine ratio though this is not as easy as it sounds, either. One needs to get an idea of the “baseline” urine protein:creatinine ratio, which means that at least a couple of samples should be checked. (The International Renal Interest Society recommends running the ratio on 3 samples over a two week period.) After this, how often the ratio should be rechecked depends on how the patient is doing and how the serum creatinine level is doing.</p>
<p><strong>The urine protein:creatinine ratio varies by up to 30% above or below<br />
“baseline” as a matter of course. A significant change in the ratio caused by<br />
disease progression (up) or response to therapy (down) must be greater than 30%.</strong></p>
<p><strong>If Intervention Is Recommended, What Does that Mean?</strong></p>
<p>There are several aspects to treatment and some or all of them may be instituted depending on the needs of the patient.</p>
<p><em>Low protein, low sodium diet</em><br />
Most commercial renal diets would fit in this category. It seems paradoxical that a disease that causes body protein to be lost would be treated with a protein-restricted diet but, in fact, supplementing protein causes albumin to drop faster.</p>
<p><em>ACE inhibitor</em><br />
These medications have been shown to reduce renal protein loss. Typically enalapril is recommended for dogs and benazepril is recommended for cats. These medications inherently reduce blood flow to the kidneys, so care must be taken in patients with elevated creatinine ratios to be sure the uremia does not worsen. Lower doses are used and monitoring becomes more important.</p>
<p><em>Aspirin<br />
</em>Aspirin in low doses can be used to reduce the tendency of blood to clot by inactivating blood platelets. Again, it is important to use low doses so as not to disturb the kidney’s circulation by disrupting the prostaglandin balance (which could happen with anti-inflammatory doses of aspirin typically used for pain). Patients where nephrotic syndrome is a concern (see below) would definitely need to be concerned about increased blood clotting tendency.</p>
<p>Omega 3 fatty acid supplementation<br />
Most commercial renal diets are fortified with omega 3 fatty acids. These anti-inflammatory fats have been shown to improve survival of dogs with renal disease. It is still unclear how helpful they are for cats but studies are ongoing.</p>
<p><strong>Nephrotic Syndrome</strong></p>
<p>In severe cases of glomerular disease, a complication called nephrotic syndrome can result due to the extreme urinary protein loss. Patients with nephrotic syndrome develop:</p>
<p>• High blood pressure<br />
• Tendency to form abnormal blood clots<br />
• Edema (swelling) especially of the legs and potentially fluid accumulation in a body cavity.</p>
<p>Nephrotic syndrome is defined as the combination of: 1) significant protein loss in urine, 2) low serum albumin, 3) edema or other abnormal fluid accumulation, and  4) elevated blood cholesterol level. This is a severe complication and suggests a poor prognosis especially if creatinine levels are elevated in the blood. Diuretics may be needed to supplement the other treatments listed above.</p>
<p><strong>Further Resources</strong></p>
<p>Other web pages on this subject that might be helpful:<br />
<a href="http://courses.vetmed.wsu.edu/vm552/urogenital/gn.htm" target="_blank">http://courses.vetmed.wsu.edu/vm552/urogenital/gn.htm</a><br />
A bit technical as it is meant as veterinary student education but still has excellent detail.</p>
<p><strong>Renal Amyloidosis: The Other Glomerular Disease</strong></p>
<p>There is an additional glomerular disease that bears mentioning and this is renal amyloidosis. Here instead of antigen:antibody complexes damaging the tender glomerular membranes, an abnormal protein called amyloid is deposited in the kidney. This condition is far less treatable and more rapidly progressive. We hope to have a supplemental section on this special situation in the near future.</p>
<p><em>Date Published: 12/30/2002 1:07:00 PM<br />
Date Reviewed/Revised: 09/25/2007<br />
</em></p>
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